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Liver Cancer

Liver Cancer, also known as hepatic cancer, originates in the cells of the liver—a vital organ responsible for detoxification, protein synthesis, metabolism, and digestion-related biochemical production.

Liver Cancer

Overview of Liver Cancer

Liver Cancer, also known as hepatic cancer, originates in the cells of the liver—a vital organ responsible for detoxification, protein synthesis, metabolism, and digestion-related biochemical production. The most common form of this cancer starts in the hepatocytes, the main liver cell type, and is known as Hepatocellular Carcinoma (HCC). Early detection is key, as liver cancer can spread rapidly if untreated.

How Liver Cancer Develops

Liver cancer occurs when healthy cells undergo genetic mutations, disrupting normal cell functions. These mutated cells begin to multiply uncontrollably, forming tumors. If left untreated, these tumors can invade surrounding tissues and spread (metastasize) to other organs. Causes of DNA mutations are often linked to chronic liver diseases, infections, and environmental exposures.

Causes & Risk Factors

  • Chronic Hepatitis B or C Infections: Long-term viral infections can lead to liver inflammation and damage, increasing cancer risk.

  • Cirrhosis: Often resulting from alcohol abuse or viral hepatitis, cirrhosis leads to scarred liver tissue and a higher cancer risk.

  • Aflatoxin Exposure: Toxins from mold-contaminated grains or nuts.

  • Alcohol Abuse: Chronic excessive drinking damages liver cells and may cause cancer.

  • Non-Alcoholic Fatty Liver Disease (NAFLD): Linked to obesity, diabetes, and metabolic syndrome.

  • Genetic Conditions: Diseases like hemochromatosis increase iron in the liver, promoting cancer.

Stages & Grades of Liver Cancer

Stages:

  • Stage I: Single tumor, no blood vessel involvement.

  • Stage II: Single or multiple tumors; one may involve blood vessels.

  • Stage III: Multiple tumors; at least one invading a major blood vessel or adjacent organs.

  • Stage IV: Metastasis to lymph nodes or distant organs.

Grades:

  • Grade 1: Low-grade, cells appear normal and grow slowly.

  • Grade 2: Intermediate, cells somewhat differ from normal.

  • Grade 3: High-grade, cells appear abnormal and grow aggressively.

Types of Liver Cancer

  • Hepatocellular Carcinoma (HCC): Most common; originates in hepatocytes.

  • Intrahepatic Cholangiocarcinoma: Originates in bile ducts within the liver.

  • Hepatoblastoma: A rare childhood liver cancer, usually in children under 3.

  • Angiosarcoma: Rare cancer beginning in liver blood vessels.

Symptoms of Liver Cancer

  • Unexplained weight loss

  • Decreased appetite

  • Persistent upper abdominal pain or swelling

  • Jaundice (yellowing of skin and eyes)

  • Nausea, vomiting

  • General fatigue and weakness

  • Chalky, white-colored stools

What to Do When You Notice Symptoms

If you or a loved one experiences these symptoms, especially with known risk factors, consult a medical professional immediately. Konkan Cancer Center offers timely screening and expert consultations for early detection and intervention.

When to Consult a Liver Cancer Specialist

Patients with liver disease, hepatitis infections, or the above symptoms should seek evaluation from specialists at Konkan Cancer Hospital. Our experienced oncologists will guide you through diagnosis and treatment planning.

Diagnostic Tests for Liver Cancer

  • Blood Tests: AFP (Alpha-Fetoprotein) is a key liver cancer marker.

  • Liver Function Tests: To evaluate overall liver health.

  • Imaging: Ultrasound, CT, and MRI to detect tumors and determine extent.

  • Biopsy: A definitive test involving tissue sample examination under a microscope.

Konkan Cancer Center integrates these tests for a comprehensive diagnostic approach to confirm liver cancer.

What to Do After a Diagnosis

Being diagnosed with liver cancer is a challenging moment. At Konkan Cancer Center, our care team provides emotional, medical, and logistical support. We build a personalized treatment plan combining medical excellence with compassionate care. Counseling and support groups are available to help patients and families cope.

Treatment Options for Liver Cancer at Konkan Cancer Center

  • Surgery: Includes partial hepatectomy or complete liver transplant in eligible patients.

  • Ablation Therapy: Minimally invasive options like RFA or microwave ablation target tumors without major surgery.

  • Embolization Procedures: TACE (Transarterial Chemoembolization) and radioembolization block the blood supply to the tumor.

  • Targeted Therapy: Advanced drugs like sorafenib and lenvatinib inhibit cancer cell pathways.

  • Immunotherapy: Drugs like nivolumab or pembrolizumab enhance the immune system’s cancer-fighting ability.

  • Radiation Therapy: Used selectively for non-surgical cases or advanced tumors.

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Gold Standard Treatment & Why

Surgical resection or liver transplantation is considered the gold standard for patients with early-stage Liver Cancer and good liver function. For inoperable or advanced cases, targeted therapies and immunotherapies offer prolonged survival and improved quality of life.

Who to Consult at Konkan Cancer Hospital (KCH)

Konkan Cancer Center offers a multidisciplinary team including hepatologists, oncologists, cancer surgeons, radiologists, and nutritionists. This ensures every patient receives expert, individualized treatment. Call us today to book a consultation.

Liver Cancer Prognosis

Survival rates for Liver Cancer depend on early detection, liver function, treatment efficacy, and overall health. With timely care at Konkan Cancer Center, even advanced cases have improved outcomes. Regular follow-ups and lifestyle modifications play a key role in long-term prognosis.

Gold Standard Treatment & Why

Surgical resection or liver transplantation is considered the gold standard for patients with early-stage Liver Cancer and good liver function. For inoperable or advanced cases, targeted therapies and immunotherapies offer prolonged survival and improved quality of life.

FAQs – Liver Cancer at Konkan Cancer Hospital (KCH)

Weight loss, fatigue, and upper abdominal discomfort.

Through blood markers (AFP), imaging, biopsy, and liver function tests.

Yes. Prevent hepatitis B and C, limit alcohol, and maintain a healthy weight.

These may include fatigue, nausea, and liver function changes depending on the therapy.

It varies. Early-stage patients have higher survival with prompt treatment.

Yes. Continuous monitoring and follow-ups are essential.

Some may support wellbeing, but always consult your oncologist first.

 Konkan Cancer Center specialists evaluate your condition to design a customized treatment.

Counselling, nutritional planning, patient navigation, and support groups.

Contact Konkan Cancer Hospital Today If you or your loved one has signs or a diagnosis of Liver Cancer, connect with Konkan Cancer Hospital for expert care. Our team is committed to helping you fight cancer with compassion, cutting-edge therapies, and world-class infrastructure. Book your appointment now.

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