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Pancreatic Cancer

Pancreatic cancer is a life-threatening malignancy that arises in the tissues of the pancreas, a vital organ located behind the stomach.

Pancreatic Cancer

Overview of Pancreatic Cancer

Pancreatic cancer is a life-threatening malignancy that arises in the tissues of the pancreas, a vital organ located behind the stomach. The pancreas performs dual functions: it helps with digestion by producing enzymes and regulates blood sugar by releasing hormones such as insulin and glucagon. Pancreatic cancer develops when abnormal cells in the pancreas begin multiplying uncontrollably and form a tumor.

Most pancreatic cancers begin in the ducts (exocrine cells), but some may start in hormone-producing endocrine cells. Due to the organ’s deep location and non-specific early symptoms, pancreatic cancer is often diagnosed at an advanced stage. Konkan Cancer Hospital offers advanced diagnostic and treatment solutions to improve patient outcomes.

How Does Pancreatic Cancer Happen?

The development of pancreatic cancer is often linked to genetic mutations—either inherited or acquired. These mutations disrupt normal cell function, causing cells to multiply uncontrollably and resist natural cell death. Pancreatic ductal adenocarcinoma (PDAC) is the most common type, originating in the lining of the pancreatic ducts. Less commonly, neuroendocrine tumors can form in hormone-producing cells.

Causes & Risk Factors

Understanding the risk factors is crucial for prevention and early detection. The major contributors include:

  • Age: Risk increases after age 65.

  • Smoking: Cigarette smoking nearly doubles the risk.

  • Genetic Predisposition: Family history and certain genetic syndromes (BRCA mutations, Lynch syndrome) raise susceptibility.

  • Chronic Pancreatitis: Long-term inflammation of the pancreas significantly heightens risk.

  • Diabetes: Particularly type 2 diabetes has been associated with an elevated risk.

  • Obesity & Diet: High intake of red/processed meats and low physical activity increase risk.

  • Exposure to Chemicals: Certain workplace exposures to dyes or pesticides may contribute.

Signs & Symptoms

Pancreatic cancer is often called a “silent disease” due to the absence of early warning signs. As the tumor grows, patients may notice:

  • Jaundice: Yellowing of the skin and eyes due to blocked bile ducts.

  • Upper Abdominal Pain: Pain that may radiate to the back.

  • Unexplained Weight Loss: Sudden, significant weight loss.

  • Loss of Appetite: Decreased desire to eat.

  • Nausea & Vomiting: Often caused by a tumor pressing on the stomach.

  • Fatigue & Weakness: Persistent tiredness.

If you experience any of these symptoms, consult the experts at Konkan Cancer Hospital for immediate evaluation.

+91 8080485895
+91 7588783924

When to See a Specialist?

If symptoms persist for more than two weeks or worsen, seek medical advice immediately. A gastrointestinal oncologist or surgical oncologist at Konkan Cancer Center can perform detailed investigations and guide you with the right care pathway.

Diagnostic Tests & Procedures

Timely and accurate diagnosis is essential for effective treatment. At Konkan Cancer Hospital, we offer a comprehensive range of diagnostics:

  • Imaging Tests: Contrast-enhanced CT, MRI, and PET scans to visualize tumor size and spread.

  • Endoscopic Ultrasound (EUS): Allows precise imaging and guided biopsy.

  • Biopsy: Fine Needle Aspiration (FNA) to confirm cancer type.

  • Blood Tests: Tumor markers like CA 19-9 are used for diagnosis and monitoring.

Gold Standard: A biopsy remains the gold standard for confirming pancreatic cancer, offering histopathological insights that guide treatment planning.

What To Do When Diagnosed?

A diagnosis of pancreatic cancer can be emotionally and physically overwhelming. At Konkan Cancer Hospital, we follow a compassionate and patient-centric approach:

  1. Specialist Consultation: Understand your diagnosis and prognosis in detail.

  2. Second Opinion (Optional): Explore all options.

  3. Multidisciplinary Planning: Oncologists, surgeons, and radiologists collaboratively build a personalized treatment strategy.

Available Treatments for Pancreatic Cancer

The treatment approach depends on the tumor’s size, location, stage, and whether it has spread. Our offerings include:

  • Surgery:

    • Whipple Procedure (Pancreaticoduodenectomy): For tumors in the pancreatic head.

    • Distal Pancreatectomy: For tumors in the body/tail of the pancreas.

    • Total Pancreatectomy: Rare, for extensive disease.

  • Radiation Therapy: High-energy X-rays target and destroy cancer cells.

  • Chemotherapy: Systemic drugs like Gemcitabine, FOLFIRINOX to halt cancer growth.

  • Targeted Therapy: Drugs like Erlotinib target genetic mutations in cancer cells.

  • Immunotherapy: Experimental in pancreatic cancer but used selectively in clinical trials.

Gold Standard Treatment: For localized and resectable tumors, surgery (especially the Whipple procedure) remains the best chance for long-term survival, often supplemented with chemotherapy and/or radiation.

Whom Should You Consult?

Our team at Konkan Cancer Hospital includes:

  • Surgical Oncologists specializing in pancreatic resections.

  • Medical Oncologists for chemotherapy and immunotherapy planning.

  • Radiation Oncologists using the latest radiotherapy protocols.

  • Nutritionists & Palliative Care for holistic recovery.

Most Asked FAQs on Pancreatic Cancer

Jaundice, upper abdominal pain, and weight loss. Many patients are asymptomatic in early stages.

Through imaging (CT, MRI), biopsy, EUS, and tumor marker blood tests.

Surgery, chemotherapy, radiation therapy, targeted therapy, and immunotherapy.

If detected early and surgically removed, there is a chance of cure. Advanced stages are more challenging.

Survival rates depend on stage at diagnosis. Early detection leads to better outcomes.

We offer cutting-edge pancreatic cancer care with a dedicated GI oncology unit, experienced team, and patient-centered approach.

Take the First Step Toward Healing At Konkan Cancer Hospital, we are committed to fighting pancreatic cancer with precision, compassion, and care. Contact us today at +91 80804 85895 or visit our website to book a consultation. Your health is our priority.

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